Endocrine Abstracts

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is an inherited syndrome characterized mainly by the association of: Primary hyperparathyroidism (PHP), gastro-entero-pancreatic tumors (GEP) and pituitary tumors. The aim of our work is to specify the particularities of PHP in MEN1 among Tunisian population.Patients & Methods: It is a retrospective descriptive study of 7 cases of MEN1, including 3 familial cases, during a 28-year period.<p...

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary syndrome that should be considered when different endocrine tumors are associated in an individual or familial context. We report the observation of a Tunisian family, two sisters and a brother.Observations: Patient1: a 31 years old female, followed for multinodular goiter, was hospitalized for a left maxillary tumefaction associated with headache and blurred vision. Investigat...

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a genetic disease that predisposes to the development of both hyperplastic and tumorous lesions of the endocrine glands, in particular parathyroid, pancreatic and pituitary. Thus we report our case.Observation: An 18-year-old male patient was hospitalized for severe hypoglycemia mistakenly treated as epileptic seizures. The etiological investigation concluded to a benign multiple insulinoma, con...

Introduction: Multiple endocrine neoplasia (MEN) is a group of inherited syndromes of autosomal dominant transmission characterized by the development of endocrine tumors.Materials and methods: It is a retrospective study collecting data of 9 patients with MEN, during a 30-year period.Results: The mean age at diagnosis was 34.6 years with a clear female predominance. The majority of our patients were from Gabes (4 cases). Seven pat...